Bio-identical hormones can be administered orally, topically, by injection or with subcutaneous implants. All these methods of delivery are effective, but each has its particular benefits and indications. For instance, micronized progesterone is most effective when given orally or sublingually. However, when given orally, it can cause drowsiness. For a woman suffering with sleep issues, I might prescribe oral progesterone at bedtime, to take advantage of this “side-effect”.

An Office Procedure

Many patients are specifically interested in hormone pellet therapy. Hormone pellet implantation is a procedure for hormone replacement that has been around since the 1970s. Bio-identical hormone pellets are administered subcutaneously – that is, they are injected under the skin, where they release directly into the bloodstream over a period of 3 to 5 months. Insertion is a simple office procedure.

Gradual Release Over Time

Pellet therapy is convenient and has comparable efficacy to pills, injections, creams and gels. The difference is that hormone management is all about achieving balance. Pellet therapy avoids the pitfalls of patient error, and offers a gradual and reliable release of hormones for a sustained period of time.